Euclid Avenue is a major street in Cleveland, Ohio. It runs northeasterly from Public Square in Downtown Cleveland, passing Playhouse Square and Cleveland State University, to University Circle,  Maltz Performing Arts Center (formerly the Temple Tifereth Israel). The street runs through the suburbs of East Cleveland, Euclid, and Wickliffe, to Willoughby as a part of U.S. Route 20 and U.S. Route 6. The HealthLine bus rapid transit line runs in designated bus lanes in the median of Euclid Avenue from Public Square to Louis Stokes Station at Windermere in East Cleveland.